Lactate dehydrogenase levels raised (plasma or serum)

Abstract Usually CPK, CK-MB and lactate dehydrogenase (LDH) enzymes
are measured in blood during the period of myocardial infarction.
The changes in LDH assay indicates duration of the infarction.
The level of lactate dehydrogenase is 500 times greater in tissue
than those found in serum. A small mass of damaged tissue causes
leakage of enzyme and increases its level in serum.
Any cause of tissue break down/hemolysis which is sufficiently
severe can produce LDH pattern similar to that in myocardial infarction.
We report this case of small bowel volvulus showing significant increase
in LDH.
It may be due to tissue necrosis which increases the level of LDH in serum.

Uday Kumar1, Anand Sharan1 and Shaheena Kamal1 Contact Information
(1) Dept. of Clinical Biochemistry, IGIMS, Sheikhpura, 800 014 Patna